NMD-VCell Research Workbench Module: Data & API · evidence-to-experiment workflow NMD = neuromuscular disorders
Research evidence only 21 observed HepG2 perturbations 0 independent DMD replications Boundary & release
Observed HepG2 perturbations with limited external myogenic context No validated DMD perturbation prediction v1.0.0-database-resource Frozen 25 Jul 2026 Schema 1.1 Model ridge-safe-v2.3 Benchmark repeated-fold-v2.2 Build EA-20260729-19 DOI pending Open evidence boundary →

Dataset Catalog

Find data by biological role, not by file name.

Disease, cell type, perturbation, time, endpoints, scale, candidate coverage and allowed use are explicit for every current dataset.

Interpretation rule. A dataset can qualify context, trajectory, disease correction or assay design without becoming direct evidence that a displayed candidate perturbation works in DMD.
internal-release-substrateObserved HepG2 CRISPRi candidate responses
Disease / role
Context-limited; not DMD
Cell type
HepG2
Perturbation
CRISPRi single-gene
Time
Frozen endpoint aggregate
Size
21 governed candidate aggregates
Candidate coverage
21/21

Permitted use: Direct same-context perturbation observation

Internal release licence pending institutional approval

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GSE293514Human myoblast fusion CRISPR screen
Disease / role
Muscle context; not DMD rescue
Cell type
Human myoblast
Perturbation
Knockout screen
Time
Publication endpoint
Size
9/21 candidates represented in library
Candidate coverage
9/21; 0 current fusion hits

Permitted use: External muscle-context screen (L3a), not replication

Source repository and publication terms apply; verify at accession

Open source accession →
GSE272233DMD-locus CRISPR-correction transcript reference
Disease / role
Duchenne muscular dystrophy
Cell type
Patient-derived and corrected cellular models
Perturbation
DMD-locus correction
Time
Study endpoint
Size
21 samples; 3 per reported group
Candidate coverage
Candidate transcripts observed; no candidate perturbation

Permitted use: Orthogonal disease-correction reference

Source repository and publication terms apply; verify at accession

Open source accession →
GSE52529Human myogenic differentiation time course
Disease / role
Non-disease trajectory reference
Cell type
Primary human skeletal myoblast
Perturbation
None
Time
0, 24, 48 and 72 hours
Size
271 cells
Candidate coverage
20/21 measured

Permitted use: Unperturbed trajectory reference only

Source repository and package terms apply; verify at accession

Open source accession →
GSE133344CRISPRa single and combinatorial calibration reference
Disease / role
Non-muscle method calibration
Cell type
K562
Perturbation
CRISPRa singles and pairs
Time
Study endpoint
Size
287 perturbations; 112 singles; 132 pairs
Candidate coverage
20/21 present as expression features

Permitted use: Method calibration only; not muscle/DMD overexpression evidence

Source repository and publication terms apply; verify at accession

Open source accession →