{
  "schema": "nmd-vcell-reviewer-guided-tour/1.0",
  "resource_release": "v1.0.0-database-resource",
  "evidence_freeze": "2026-07-25",
  "interface_build": "EA-20260729-15",
  "route": "/resource/reviewer-quickstart",
  "visualization_type": "pipeline_style_reviewer_guided_tour_not_sankey_or_alluvial",
  "flow_semantics": "Single-gene and single-reviewer navigation path; step widths do not encode counts or evidence strength.",
  "steps": [
    {
      "step_index": 1,
      "label": "1 · Search gene",
      "title": "Start with one typed gene record",
      "route": "/resource/genes/",
      "expected_visual_result": "Gene visual profile",
      "reviewer_task": "Inspect identifiers, evidence ceiling, DMD prior/source agreement, muscle-expression context and the decision-blocking gap.",
      "boundary_check": "A single gene view reorganizes frozen fields only; it does not create a new rank."
    },
    {
      "step_index": 2,
      "label": "2 · Compare candidates",
      "title": "Contrast a small candidate set",
      "route": "/resource/comparison/CMP-20260726-A9A727B87722/",
      "expected_visual_result": "Comparison visual dashboard",
      "reviewer_task": "Open the ZNF133/MON1A/GFOD2 comparison or paste a list to inspect mapped evidence dimensions side by side.",
      "boundary_check": "Input order is preserved; no winner, score, cluster or therapeutic priority is computed."
    },
    {
      "step_index": 3,
      "label": "3 · Build Study Card",
      "title": "Generate the next-experiment route",
      "route": "/resource/planner",
      "expected_visual_result": "Planner visual builder",
      "reviewer_task": "Resolve a gene into current action, evidence state, assay route and registration gaps before opening a stable card.",
      "boundary_check": "The Planner is a pipeline-style route, not an intervention recommender."
    },
    {
      "step_index": 4,
      "label": "4 · Inspect visual card",
      "title": "Read the stable Study Card object",
      "route": "/resource/study-card/ZNF133",
      "expected_visual_result": "Study Card visual summary",
      "reviewer_task": "Audit the frozen evidence route, bioinformatics snapshot, design route and registration gap map.",
      "boundary_check": "Cards remain DRAFT until required fields are registered and checksummed."
    },
    {
      "step_index": 5,
      "label": "5 · Validate/register",
      "title": "Confirm gates before any claim expansion",
      "route": "/resource/workbench",
      "expected_visual_result": "Validation and registry gates",
      "reviewer_task": "Inspect readiness gates, registry lifecycle, prospective outcome scaffolds and external release blockers.",
      "boundary_check": "P1/P2 prediction claims remain locked; formal v1.0 still requires external gates."
    }
  ],
  "examples": [
    {
      "gene": "ZNF133",
      "branch": "muscle_context_assay",
      "stable_study_card": "/resource/study-card/ZNF133",
      "review_value": "full muscle-assay evidence-to-experiment route"
    },
    {
      "gene": "CPEB1",
      "branch": "verify_expression",
      "stable_study_card": "/resource/study-card/CPEB1",
      "review_value": "expression-feasibility branch before perturbation escalation"
    },
    {
      "gene": "GFOD2",
      "branch": "external_evidence_audit_hold",
      "stable_study_card": "/resource/study-card/GFOD2",
      "review_value": "provisional external-evidence hold without silent promotion"
    }
  ],
  "claims_not_made": [
    "candidate ranking",
    "target score",
    "therapeutic efficacy",
    "clinical decision support",
    "P1/P2 disease-prediction unlock",
    "formal v1.0 authorization"
  ],
  "boundary": "v1.0 is a database and evidence-governance release; it is not a validated disease-prediction or clinical decision-support release."
}